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Development and testing of a game-based digital intervention for working memory training in autism spectrum disorder Permalink
Published in Scientific Reports, 2021
This study introduces and evaluates a game-based digital intervention aimed at improving working memory in individuals with autism spectrum disorder.
Recommended citation: Wagle, S., Ghosh, A., Karthic, P., Ghosh, A., Pervaiz, T., Kapoor, R., Patil, K., & Gupta, N. (2021). Development and testing of a game-based digital intervention for working memory training in autism spectrum disorder. *Scientific Reports, 11*(1), 13800. https://doi.org/10.1038/s41598-021-93258-w
Computational insights into mRNA and protein dynamics underlying synaptic plasticity rules Permalink
Published in Molecular and Cellular Neuroscience, 2023
The paper presents computational models to understand the roles of mRNA and protein dynamics in synaptic plasticity, highlighting the importance of local translation.
Recommended citation: Wagle, S., Kraynyukova, N., Hafner, A. S., & Tchumatchenko, T. (2023). Computational insights into mRNA and protein dynamics underlying synaptic plasticity rules. *Molecular and Cellular Neuroscience, 125*, 103846. https://doi.org/10.1016/j.mcn.2023.103846
An Unguided, Computerized Cognitive Behavioral Therapy Intervention (TreadWill) in a Lower Middle-Income Country: Pragmatic Randomized Controlled Trial Permalink
Published in Journal of Medical Internet Research, 2023
This RCT evaluates TreadWill, an unguided computerized CBT program, finding it effective in reducing depression in a lower middle-income country.
Recommended citation: Ghosh, A., Cherian, R. J., Wagle, S., Sharma, P., Kannan, K. R., Bajpai, A., & Gupta, N. (2023). An Unguided, Computerized Cognitive Behavioral Therapy Intervention (TreadWill) in a Lower Middle-Income Country: Pragmatic Randomized Controlled Trial. *Journal of Medical Internet Research, 25*, e41005. https://doi.org/10.2196/41005
SpyDen: Automating molecular and structural analysis across spines and dendrites Permalink
Published in Biofinrmatics (Oxford Press), 2024
SpyDen introduces an automated platform to analyze spine and dendrite structures, streamlining molecular neuroanatomical analysis.
Recommended citation: Eggl, M. F., Wagle, S., Filling, J. P., Chater, T. E., Goda, Y., & Tchumatchenko, T. (2024). SpyDen: Automating molecular and structural analysis across spines and dendrites. https://doi.org/10.1093/bioinformatics/btaf339
An integrative model of AMPA receptor trafficking reveals the central contribution of local translation in subtype-specific kinetics Permalink
Published in bioRxiv, 2025
This study proposes a model for AMPA receptor trafficking, showing how local translation governs kinetic properties across receptor subtypes.
Recommended citation: Wagle, S., Kracht, M. K., Bührke, A., Acker-Palmer, A., Kraynyukova, N., Hafner, A.-S., Schuman, E. M., & Tchumatchenko, T. (2025). An integrative model of AMPA receptor trafficking reveals the central contribution of local translation in subtype-specific kinetics. *bioRxiv*. https://doi.org/10.1101/2025.02.08.637220